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Updates to the Largest Markush Search Databases: MMS and MARPAT

[tweetmeme source=”Intellogist” only_single=false] Do you know the best resources for searching Markush chemical structures in patent documents? If you need to freshen up your Markush search skills, then you’re in luck.  Intellogist Reports on two of the largest sources of Markush data, Merged Markush Service (MMS) and MARPAT on STN, have both been fully updated, and we’ll look at some of the most important recent changes to these databases. The Merged Markush Service (MMS) is a generic chemical structure file which is linked to two bibliographic data files, the Derwent World Patents Index, produced by Thomson Derwent, and the Pharm (formerly Pharmsearch) file, produced by the French Patent Office (INPI).  MARPAT, produced by CAS and FIZ-Karlsruhe,  contains only patents which have been indexed into the CAplus database and which generically disclose/claim chemical structures.

Last week we looked at major updates to the STN platform, on which you can search MARPAT.  The content of the MARPAT database has undergone a lot of recent improvements, with new country coverage, more structure images, and additional backfile coverage from 1987 added to the file. Meanwhile, users can now search the MMS file through a new platform produced by ChemAxon.  After the jump, we’ll look at updates to both the search features and content of MARPAT and MMS.

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ChemAxon: Revolutionizing Generic Chemical Structure Searches

[tweetmeme source=”Intellogist” only_single=false] Searching for Markush structures is a difficult task, and professional searchers need training and experience to search competently for Markush structures in the MMS database.  Markush structures originate in patent claims (Markush claims) for generic chemical compounds, and a single Markush structure could correspond to thousands of different specific chemical structures (enumerations).  The Merged Markush Service (MMS) was created in 1998, after the merger of two generic structure databases owned by Thomson Derwent and the French Patent Office (INPI).  Until recently, the MMS file was only accessible via the Questel Imagination platform or the STN Express platform, and both platforms require command line searching in order to draw, search, and display structures.  The chemical drawing tool Topfrag is available through Questel, but this program must be purchased.

Luckily, users now have a third option for searching MMS: through JChem  and MarvinSketch, created by  ChemAxon.  Thomson Reuters recently partnered with ChemAxon to make Markush DARC (MMS) records available on the JChem platform.  Continue reading to discover the unique search, display, and analytic capabilities of ChemAxon products!

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